Consider a Calabi-Yau manifold which arises as a member of a Lefschetz pencil of anticanonical hypersurfaces in a Fano variety. The Fukaya categories of such manifolds have particularly nice properties. I will review this (partly still conjectural) picture, and how it constrains the field of definition of the Fukaya category.
The problems come in two flavors.
Extrinsic Flavor: Given a point cloud in R^N sampled from an unknown probability density, how can we decide whether that probability density is concentrated near a low-dimensional manifold M with reasonable geometry? If such an M exists, how can we find it? (Joint work with S. Mitter and H. Narayanan)
We use persistent homology to analyze predictions of protein folding by trying to identify global geometric structures that contribute to the error when the protein is misfolded. The goal is to find correlations between global geometric structures, as measured by persistent homology, and the failure to predict the correct folding. This technique could be useful in guiding the energy minimization techniques to the correct minimum corresponding to the desired folding.